You appear to be looking at the global CommCell settings.
That will encrypt all copies.  You can also encrypt just HSX.
 

Thanks,
Scott
 

Hi @Scott Moseman Thank you so much for the response. Would that create latency when the backups run? And how to I tell if my data are encrypted?  

The performance impact is probably a rounding error.  I have never heard from anyone about a performance impact after enabling encryption.  It’s not going to be noticeable.

I’m not sure how to tell if data is encrypted.  I think one of the backup job reports will have a flag to let you know the job was encrypted.

Thanks,
Scott
 

Thank you so much @Scott Moseman.