Hello @jego
The cost and availability of SSD storage now days means it is very easy to get a few TB available and dedicated to a Media agent for the DDB its self.
The DDB does not take up much space when compared to the disk library size but has high performance requirements. you will always have IO related issues with you are just using a datastore presented disk from your day to day use array.
I would guess you could get some improvement by making the change to MBR but in realistically it will be a tiny % increase when compared to just getting a SSD for the MA.
Kind regards
Albert Williams