How to set VM filters via CLI for Backupset or Subclient

Hello All.  We have 4700 VMs with a couple dozen backups sets where I need to exclude VMs that don't require a backup.  e.g. AD, DNS, VDI, etc.  I know I can manually open each backupset and create a VM Filter, but I'm thinking there's a better way.

It would be great to have a "global filter" for VMs similar to WinFS and LinuxFS clients.
Is there a way to utilize PowerShell or CV CLI?

Or is there some other way I’m not thinking and I’m making this harder than it needs to be?

Thanks!
Dan

PS after typing this I'm thinking I should have less backupsets…  but still interested in your thoughts.  :)