Setting up a new Windows Server as a Media Agent server with disk pool storage

I have a Dell PE R740xd that we are going to use as a replacement Media Agent server. This Media Agent server will be used for our VMware backups. I have two mirrored drives for the OS, Two mirrored drives for the Index Cache and two mirrored drives for the Deduplication Database. I have 8, 4TB drives that will make up my disk pool. What is the best way to configure these 8 drives to get the best read\write performance? We are running Windows Server 2019.